Generic drug of Cerazette
Therapeutic class: Contraception and termination of pregnancy
active ingredients: Desogestrel
laboratory: Besins International
Dosage ANTIGONE Ge 75 micrograms Tablet box of 1 plate 28
· Pregnancy known or suspected.
· Evolutionary venous thromboembolic accidents.
· Presence or history of severe liver disease, as long as the liver function parameters have not returned to normal.
· Known or suspected tumors sensitive to sex steroids.
· Unexplained vaginal haemorrhage.
Hypersensitivity to the active substance or to any of the excipients listed in the Composition section.
Side effects Antigone Ge 75 Micrograms
The most frequently reported adverse reaction in clinical trials is the irregularity of bleeding. Up to 50% of women using desogestrel reported irregular bleeding. As desogestrel causes ovulation inhibition close to 100%, unlike other progestin-only pills, irregular bleeding is more common than with these other pills. In 20% to 30% of women, bleeding may occur more frequently, whereas in 20% of women bleeding may be less frequent or absent altogether. Vaginal bleeding may also be longer. After a few months of treatment, bleeding tends to be less frequent. Information, tips and a bleeding tracker can help women better accept them.
The other most commonly reported adverse reactions (> 2.5% frequency) in clinical trials with desogestrel are: acne, mood changes, mastodynia, nausea, and weight gain. The undesirable effects listed in the table below were considered by the investigators to be causally certain, probable or possible with the treatment.
System Organ Class (MedDRA) version 12.0
Frequency of adverse effects
(≥1 / 100 to <1/10)
(≥1 / 1000 to <1/100)
(≥1 / 10, 000 to <1/1000)
Infections and infestations
Mood modification, decreased libido
Nervous system disorders
Contact lens intolerance
Skin and subcutaneous tissue disorders
Rash, hives, erythema nodosum
Disorders of reproductive organs and breast
Mastodynia, irregular bleeding, amenorrhea
Dysmenorrhea, ovarian cyst
General disorders and administration site conditions
Breast discharge may occur during the use of ANTIGONE. In rare cases, ectopic pregnancies have been reported (see Warnings and Precautions ).
In women using oral contraceptives (combined) a number of (serious) side effects have been reported. They include venous thromboembolic disorders, arterial thromboembolic disorders, hormone-dependent tumors (eg liver tumors, breast cancer) and chloasma, some of which are detailed in the Warnings and Precautions for Use section .