Chondrocalcinosis: the causes

The precise causes of chondrocalcinosis are still unknown. In most cases, it is said to be idiopathic, that is to say without known cause.

It is an arthropathy caused by deposits of calcium pyrophosphate in the joints (the most affected are those of the knees and wrists).

The frequency of chondrocalcinosis increases with age: it never appears before the age of 30, and usually after the age of fifty. This pathology is often associated with osteoarthritis.

There are two forms of chondrocalcinosis: primary chondrocalcinosis and secondary chondrocalcinosis.

Primary chondrocalcinosis

In case of primary chondrocalcinosis, chondrocalcinosis mainly affects the elderly, its frequency increasing with age. It affects 10 to 15% of people between 65 and 75 years, more than 25% beyond men and women combined.

Very rarely, there is a familial predisposition to chondrocalcinosis.

Secondary chondrocalcinosis

A secondary chondrocalcinosis can come from an endocrine or metabolic disease, for example:

  • hemochromatosis,
  • hyperparathyroidism,
  • chronic hypomagnesemia (severe magnesium deficiency).

It is called secondary chondrocalcinosis when it is the consequence of a pre-existing disease. This form of chondrocalcinosis is more rare, but it is necessary to look for them before 50 years. In this case, the doctor looks for other symptoms related to this metabolic pathology and prescribes additional examinations to establish an accurate diagnosis.

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Read also :

> Missing magnesium: what are the symptoms?
> Lumbar osteoarthritis: causes for treatment
> Chronic atrophic polychondritis (PCA)

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