Medicinal Products

DANTRIUM 100 mg

Generic drug of the therapeutic class: Rheumatology
Active ingredients: Dantrolene
laboratory: Norgine Pharma

capsule
box of 30
All forms

Indication

· Treatment of advanced forms of pyramidal spasticities associated with hemiplegia, paraplegia and multiple sclerosis.
Dantrolene is particularly useful in patients with good residual motility and in whom spasticity is a significant barrier to functional rehabilitation.

· Prevention of perianesthetic malignant hyperthermia.
The administration of dantrolene does not preclude the application of other general preventive measures of malignant hyperthermia.

Dosage DANTRIUM 100 mg capsule box of 30

· Treatment of advanced forms of pyramidal spasticities associated with hemiplegia, paraplegia and multiple sclerosis.
Dantrolene is particularly useful in patients with good residual motility and in whom spasticity is a significant barrier to functional rehabilitation.

· Prevention of perianesthetic malignant hyperthermia.
The administration of dantrolene does not preclude the application of other general preventive measures of malignant hyperthermia.

Against indications

· Severe hepatocellular insufficiency.

· Hypersensitivity or intolerance to gluten, due to the presence of wheat starch (gluten).

Dantrium side effects

· At the beginning of treatment, it is not uncommon to observe symptoms of central origin (somnolence, dizziness, asthenia, confusional disorders), usually regressive, which is why it is recommended to gradually increase the doses looking for the optimal dosage.

· Hepatotoxicity (see Warnings and Precautions section ): rarely at doses less than 200 mg / day.

· Digestive disorders: gastralgia, nausea, vomiting, diarrhea.

· Urinary system: possibility of incontinence by sphincteric relaxation.
An orange coloring of the urine, due to the presence of dantrolene, sometimes appears during treatment.

· Rash, rarely of acneiform appearance.

· Anaphylaxis.

· In a completely isolated way:

o haematological disorder: leukopenia, aplastic anemia, lymphoid lymphoma,

o heart failure.

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