Medicinal Products

DELTAZINE 40 mg / mL

Generic drug of the therapeutic class: Anesthesia, resuscitation, analgesics
active ingredients: Articaine
laboratory: Ato Zizine

Injectable solution for dental use
Box of 50 cartridges of 1.7 ml
All forms

Indication

Local or loco-regional anesthesia in odonto-stomatological practice.

This specialty is used especially when the use of a vasoconstrictor is not recommended.

Dosage DELTAZINE 40 mg / mL Injection solution for dental use Box of 50 1.7 ml cartridges

Reserved for adults and children from 4 years old due to the type of anesthesia not adapted before this age.

Dosage

Adult

The quantity to be injected will be adapted according to the importance of the intervention.

Typically, one half to one cartridge for routine surgery.

Do not exceed the dose of 7 mg articaine hydrochloride per kilogram of body weight.

Child (over 4 years old)

The quantity injected depends on the age, the weight of the child and the type of intervention to be performed.

The maximum dose to be expected is 5 mg of articaine hydrochloride (0.125 ml of anesthetic solution) per kilogram of body weight.

The average dose in mg of articaine hydrochloride, which can be administered in children, can be calculated as follows:

· Child's weight (in kilograms) × 1.33.

Elderly

Half of the dose reserved for adults.

Administration mode

LOCAL OR REGIONAL INJECTION INTRA-ORAL UNDER MUCOUS.

Verify that there is no vascular intrusion by repeated aspiration tests, especially during regional (truncular) anesthesia.

The injection speed must not exceed 1ml of solution per minute.

Against indications

This drug is contraindicated in case of hypersensitivity to local anesthetics or any of the components, and in the following situations:

· Severe and uncontrolled atrioventricular conduction disorders;

Epilepsy not controlled by treatment;

· Acute intermittent porphyria.

Deltazine side effects

As with all anesthetics used in odonto-stomatology, lipothymia can occur.

In case of overdose or in certain predisposed patients, the following clinical signs may be observed

· On the central nervous system :
nervousness, agitation, yawning, trembling, apprehension, nystagmus, logorrhea, headache, nausea, tinnitus. These signs of call require to ask the patient to hyperventilate, as well as a careful monitoring to prevent a possible aggravation with convulsions then depression of the CNS.

· On the respiratory system :
tachypnea then bradypnea can lead to apnea.

· On the cardiovascular system :
tachycardia, bradycardia, cardio-vascular depression with hypotension that may lead to collapse, rhythm disturbances (ventricular extrasystoles, ventricular fibrillation), conduction disturbance (atrioventricular block).
These cardiac manifestations can lead to cardiac arrest.

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