Medicinal Products

DESERNIL SANDOZ 1.65 mg

Generic Drug Therapeutic Class: Neurology-Psychiatry
active ingredients: Methysergide
laboratory: Novartis Pharma SA

Compressed
Box of 20
All forms

Indication

Treatment of migraine headaches and vascular pain of the face.

Dosage DESERNIL SANDOZ 1.65 mg Tablet Box of 20

Reserved for adults.
- The administration must be progressive: start with a half-tablet, at the evening meal, for a few days. This daily dose may be increased to 2 or 3 tablets a day, with meals. After a few weeks of treatment, look for a gradual reduction in the effective maintenance dose (see section on warnings and precautions for use).
- Continuous administration must not exceed six months.

Against indications

CONTRAINDICATED:
- Known hypersensitivity to methysergide or any of the components.
- Pregnancy: administration is contraindicated during pregnancy due to residual oxytocic activity.
- Peripheral circulation disorders, especially arterial, poorly controlled blood pressure, valvulopathy, coronary insufficiency.
- Severe renal or hepatic insufficiency.
- Temperate arteritis.
- Hemiplegic or basilar migraine.
- History of fibrosis of medicinal origin.
- Obstructive diseases of the upper urinary tract.
- Severe infectious states, cachexia.
- Association with triptans (almotriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan, eletriptan) (see section interactions).
Due to the presence of lactose, this drug is contraindicated in cases of congenital galactosemia, glucose-galactose malabsorption syndrome or lactase deficiency.
NOT RECOMMENDED :
- Breast-feeding is contraindicated during use of this medication: Due to the passage of methysergide in breast milk, breast-feeding is contraindicated while using this medication.
- Absorption of alcohol is strongly discouraged during the course of treatment.

Side effects Desernil Sandoz

- May occur:
. Nausea and vomiting, which can be reduced in case of food intake.
. Insomnia, dizziness, transient changes in mood, skin reactions (skin rashes and urticaria), edema, arterial vasoconstriction.
. Chest pain (angina), abdominal pain, cold, painful, numb extremities, with or without paresthesia and a decreased or absent pulse.
. Isolated cases of myocardial infarction have been reported, particularly in patients for whom contraindications to coronary artery disease or the use of vasoconstrictor drugs have not been respected.
- Risks of uninterrupted long-term treatment:
. Retroperitoneal fibrosis may cause obstruction of the urinary tract with dysuria or oliguria, lumbar and / or abdominal pain, circulatory failure of the lower extremities.
. Pleuropulmonary fibrosis may result in chest pain, dyspnea, rubbing or pleural effusion.
. Rare cases of pericardial fibrosis or heart valves have been reported.
- These events usually go away after stopping treatment.

Popular Posts

Category Medicinal Products, Next Article