Medicinal Products

PEDIAVEN AP-HP NEW-3 Solution for infusion Box of 10 Pockets of 250 ml

Generic drug of the therapeutic class: Anesthesia, resuscitation, analgesics
Active Ingredients: Alanine, Arginine, Aspartic Acid, Cysteine, Glutamic Acid (E620), Glycine, Histidine, Isoleucine, Leucine, Lysine, Methionine, Phenylalanine, Proline, Serine, Taurine, Threonine, Tryptophan, Tyrosine, Valine, Potassium Hydroxide ( E525), Phosphat
lab: HP Public Support

Injection solution for IV infusion
All forms

Indication

- Basic support for parenteral nutrition of the premature newborn or not, when the oral or enteral feeding is impossible, insufficient or contraindicated.
- Nitrogen supply (L-series amino acids) and electrolytes in combination with a non-protein caloric intake, more particularly in addition to a lipid infusion or a binary infusion type PEDIAVEN AP-HP NEW-1 or 2.

Dosage PEDIAVEN AP-HP NEW-3 Solution for infusion Box of 10 Pockets of 250 ml

Dosage:
- The dosage is individual and varies according to age, weight, metabolic and energy needs, as well as the patient's clinical condition and metabolic abilities.
- PEDIAVEN AP-HP NEW-NE 3 is to use:
. in addition to PEDIAVEN AP-HP NEW-NE 1 to obtain initial intakes of 1.5 g / kg / day of amino acids in order to obtain a zero nitrogen balance from the outset;
. or in addition to PEDIAVEN AP-HP NEW-1 or 2 during the administration of lipids, in order to obtain a calorico-nitrogen ratio of about 250 kcal (non-protein calories) per gram of nitrogen. As an indication, in neonates, the nitrogen energy intake should correspond to about 13% of the total energy intake, ie 0.13 g of amino acids per gram of perfused glucose and 0.36 grams of amino acids per gram of lipid infused; the optimal amino acid intake during total long-term parenteral nutrition is of the order of 3.5 g / kg / day.
- PEDIAVEN AP-HP NEW-NE 3 can be added in a PEDIAVEN AP-HP NEW-NE 1 or PEDIAVEN AP-HP NEW-NE 2 pouch at a maximum volume of 25 ml (considering the volume of the pouch), or administered separately at a maximum rate of 55 ml / kg / day.
Administration mode :
- In central or peripheral intravenous perfusion.
- Administration must be continuous 24 hours.

Against indications

- Known hypersensitivity to a component of the solution.
- Congenital abnormality of amino acid metabolism.

Adverse effects Pediaven AP-HP New-NE 3

- Potential adverse effects may occur:
. transient disruption of liver function;
. hyperphenylalaninemia in premature infants in a severe clinical condition;
. hypersensitivity reactions to certain amino acids;
. thrombophlebitis, especially if the perfusion is performed intravenously peripheral.
- In case of excessive intake of amino acids, metabolic acidosis and hyperazotemia may occur especially in cases of renal or respiratory failure.
- The appearance of any uncontrolled abnormal signs (including chills, sweating, fever, difficulty breathing) must stop the infusion. Sepsis related to the catheter should be sought.

Popular Posts

Category Medicinal Products, Next Article