Medicinal Products

PENTACOQ Powder and suspension for injectable suspension IM or SC Box of 1 vial of powder + pre-filled syringe of 0.5 ml

Generic drug of the therapeutic class: Infectiology - Parasitology
active ingredients: Powder:, Haemophilus influenzae type b polysaccharide, Tetanus protein, Suspension:, Diphtheria toxoid, Tetanus toxoid, Bordetella pertussis, Poliomyelitis virus type 1, Poliomyelitis virus type 2, Poliomyelitis virus type 3
laboratory: Sanofi Pasteur Msd

Powder and solvent for injectable suspension (IM / SC)
All forms


Joint prevention of invasive Haemophilus influenzae type b infections (meningitis, septicemia, cellulitis, arthritis, epiglottitis ...) of diphtheria, tetanus, whooping cough and poliomyelitis.
PENTACOQ does not protect against infections caused by other types of Haemophilus influenzae or meningitis of other origins.

Dosage PENTACOQ Powder and suspension for injectable suspension IM or SC Box of 1 vial of powder + pre-filled syringe of 0.5 ml

3 injections of a unit dose of vaccine (0.5 ml) spaced a month, ie following the official schedule, an injection at the age of 2, 3 and 4 months followed by the booster : one injection, one year after primary vaccination.
Administration mode :
The injection is done: in the anterolateral side of the thigh (middle third) or in the gluteal region by the intramuscular or subcutaneous route. However, due to the adsorbed nature of the TETRACOQ vaccine, the intramuscular route should be preferred to minimize reactions.

Against indications

- Hypersensitivity to any of the components of the vaccine.
- Convulsive evolutionary encephalopathies or not.
- Strong reaction occurring within 48 hours after an earlier vaccination injection:
. fever greater than or equal to 40 ° C,
. persistent screaming syndrome,
. febrile or non-febrile seizure,
. Hypotonic-hyporesponsive syndrome.
In these cases, vaccination should be continued with a vaccine not containing pertussis.
- Immediate hypersensitivity reactions following a previous injection (urticaria, angioedema, anaphylactic shock).
Do not inject intravascularly.
Do not inject intradermally.

Side effects Pentacoq

- Local reactions at the injection site: pain, erythema, induration, edema can be observed within 48 hours after vaccination and persist for several days. The formation of a subcutaneous nodule lasting several weeks may accompany these reactions. Rare cases of amicrobial abscess have been reported.
- General reactions:
Fever above 38 ° C, unusual crying within 24 to 48 hours after vaccination.
Allergic manifestations: rash, urticaria and exceptionally anaphylactic shock or angioedema.
Very rarely, episodes of hypotonia-hyporesponsiveness, persistent cry syndrome, convulsions with or without fever.
Exceptionally acute encephalopathy.
The neurological disorders following vaccination are more readily attributed to the pertussis valence.
- When administering vaccines containing the valence haemophilus type b, oedematous reactions of the lower limbs have been reported. It is edema with cyanosis or fugitive purpura, reaching the whole vaccinated member and sometimes the contralateral limb, appearing in the hours following the vaccination, can last several hours and disappearing spontaneously without sequelae. These reactions are sometimes accompanied by fever, pain and crying.

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